Strengthening and modernizing sustainable public health systems and workforce in Uganda for data science, informatics, surveys, and surveillance for timely, accurate, and integrated data for action under PEPFAR | CDC RFA JG 25 0047

Opportunity Information: Apply for CDC RFA JG 25 0047

The Centers for Disease Control and Prevention (CDC), through its Global Health Center and under PEPFAR, is offering a cooperative agreement opportunity titled "Strengthening and modernizing sustainable public health systems and workforce in Uganda for data science, informatics, surveys, and surveillance for timely, accurate, and integrated data for action under PEPFAR" (Funding Opportunity Number: CDC RFA JG 25 0047; CFDA: 93.067). The main purpose is to work closely with the Government of Uganda (GOU) and especially the Ministry of Health (MOH) to improve how health data are generated, managed, linked, analyzed, and used, with a strong emphasis on making data more timely, accurate, and integrated so that program leaders can make better decisions faster. The opportunity is positioned as a public health systems and workforce modernization effort rather than a research program, and it is explicitly not intended to fund research activities.

This funding focuses on strengthening core capabilities across data science, public health informatics, surveys, and surveillance systems that support HIV and related health programs in Uganda. A central theme is improving decision-making through better "data for action," meaning data should not just be collected and stored, but converted into practical, operational insights that can guide program improvements, resource allocation, and rapid responses to outbreaks or emerging threats. The CDC is emphasizing modernization, which typically involves improving interoperability between systems, streamlining data flows from facilities to national levels, increasing the quality and completeness of routine reporting, and building the analytic capacity needed to translate raw data into usable intelligence.

A major deliverable area is epidemic intelligence, described here as the capacity and data infrastructure needed to detect, interpret, and respond to health events in time to influence outcomes. In practice, this implies building or strengthening mechanisms that can pull together multiple data sources (for example, routine clinical data, laboratory information, case-based surveillance, and targeted surveys) and turn them into near-real-time situational awareness for decision-makers. While the opportunity text does not list specific platforms or tools, it signals an expectation for integrated approaches that connect surveillance and program monitoring data so leaders can quickly identify gaps, emerging trends, or geographic hotspots and respond accordingly, particularly for HIV and closely linked public health priorities.

The NOFO supports data generation through multiple non-research data collection approaches, including general population or targeted surveys, clinical surveillance, disease surveillance, and other structured data-collection activities designed to close specific data or knowledge gaps. The language suggests the goal is to ensure that Uganda has the right mix of routine and supplemental data sources to answer priority operational questions for HIV and related programs, such as measuring service coverage and quality, monitoring outcomes, and detecting outbreaks or changes in epidemiologic patterns that would require adjustments in programming. The key boundary is that these activities must be oriented toward public health practice and program improvement, not research.

From a partnership and implementation standpoint, the award is meant to be implemented in coordination with the GOU and MOH as the primary partner, which implies alignment with national strategies, coordination with existing national information systems, and an emphasis on sustainability within Uganda's public health system. The emphasis on workforce strengthening indicates that funding is expected to support skills development and institutional capacity so that data science and informatics capabilities are retained and used effectively within Ugandan institutions over time, rather than relying on short-term external expertise. This can include improving competencies in data management, analytics, visualization, surveillance operations, and the governance processes that ensure data quality and appropriate use.

In terms of funding and structure, this is a discretionary cooperative agreement, meaning CDC will likely have substantial programmatic involvement during implementation compared to a standard grant. CDC anticipates approximately $20,000,000 in total fiscal year funding for Year 1, subject to availability of funds, and expects to make two awards. Notably, the Award Ceiling for Year 1 is listed as $0 (none), which usually indicates that a maximum cap is not specified in the notice rather than implying no funding; applicants typically propose budgets aligned with the program scope and CDC guidance, and final award amounts depend on federal funding availability and application merit.

The opportunity is open to a broad range of eligible applicants, including various levels of government entities, public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations (including small businesses), tribal governments and organizations, and public housing authorities, with eligibility described as essentially unrestricted. The administering agency is listed as Centers for Disease Control-GHC. The opportunity was created on 2024-12-02, and the original closing date is 2025-02-18.

• The Centers for Disease Control-GHC in the health sector is offering a public funding opportunity titled "Strengthening and modernizing sustainable public health systems and workforce in Uganda for data science, informatics, surveys, and surveillance for timely, accurate, and integrated data for action under PEPFAR" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
• This funding opportunity was created on 2024-12-02.
• Applicants must submit their applications by 2025-02-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 2 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.

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