Opportunity Information: Apply for PAR 20 125

The Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional) funding opportunity (PAR-20-125) is a discretionary NIH grant led by the National Institute of General Medical Sciences (NIGMS) in collaboration with other participating NIH Institutes and Centers and the Indian Health Service (IHS). Its central purpose is to strengthen and expand tribally driven health research that is grounded in the priorities of American Indian and Alaska Native (AI/AN) communities. In practice, the program is designed to help Tribes and Tribal organizations build or enhance research centers that can both carry out meaningful studies and develop the people, systems, and partnerships needed to sustain high-quality research over time.

A key emphasis of NARCH is supporting research projects that directly address health needs identified by AI/AN communities themselves. The opportunity is structured to encourage community-relevant research agendas rather than top-down research topics, with the expectation that funded work will reflect Tribal priorities and benefit Tribal communities. The "Clinical Trial Optional" designation means applicants may propose studies that include clinical trials, but they are not required to do so; applicants can pursue a range of research approaches depending on community needs and readiness, from observational and community-based research to intervention studies where appropriate.

Beyond funding individual research studies, NARCH places strong weight on career enhancement and workforce development. This includes creating or expanding opportunities for training, mentorship, and professional growth for individuals involved in Tribal health research. The intent is to grow research capacity in a way that supports AI/AN investigators, clinicians, and community research staff, improving local expertise and helping establish a durable pipeline of people who can lead and sustain research programs aligned with Tribal health priorities.

Another major goal is infrastructure and capacity building. NARCH is meant to help participating centers strengthen the practical foundations that make research possible and competitive, such as research administration, compliance and oversight processes, data management, community engagement structures, partnerships, and other institutional supports. The funding aims to improve long-term sustainability so that Tribal research centers can become more competitive for future funding and better positioned to maintain strong research environments over time, rather than relying on short-term project-by-project support.

Eligibility is limited in a way that reflects the program's focus on Tribal leadership and sovereignty in research. Applicants must be federally recognized Native American tribal governments or eligible Tribal organizations, as described in the full funding opportunity announcement. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible. In addition, foreign components, as defined under the NIH Grants Policy Statement, are not allowed, reinforcing that the work supported under this opportunity must be carried out within allowable domestic organizational structures.

This opportunity is administered by the National Institutes of Health, with an original closing date of July 23, 2021, and a creation date of March 5, 2020. It is categorized under a broad set of public funding activity areas including education, food and nutrition, and health, and it is associated with multiple CFDA listings (including 93.121, 93.172, 93.213, 93.233, 93.279, 93.307, 93.313, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.855, 93.859, and 93.866), reflecting the cross-institute nature of NIH participation in supporting AI/AN health research and research capacity development.

  • The National Institutes of Health in the education, food and nutrition, health sector is offering a public funding opportunity titled "Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.172, 93.213, 93.233, 93.279, 93.307, 93.313, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.855, 93.859, 93.866.
  • This funding opportunity was created on 2020-03-05.
  • Applicants must submit their applications by 2021-07-23. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Native American tribal governments (Federally recognized).
Apply for PAR 20 125

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