Opportunity Information: Apply for PAR 25 441

The Native American Research Centers for Health (NARCH) Planning Grants program is a National Institutes of Health (NIH) discretionary grant opportunity designed to help eligible American Indian and Alaska Native (AI/AN) Tribal entities do the upfront planning and groundwork needed to develop strong, competitive full NARCH applications later on. It uses the R34 planning grant mechanism and is labeled "Clinical Trial Not Allowed," meaning the grant is intended for planning and preparatory activities rather than conducting clinical trials. The overall goal is to strengthen the readiness of Tribal communities and Tribal-serving organizations to build well-designed, community-informed research center proposals that can support health research capacity and address health priorities relevant to AI/AN communities.

The opportunity is specifically aimed at federally recognized AI/AN Tribes, Tribal colleges and universities, Tribal health programs, and other Tribal organizations, collectively referred to as eligible AI/AN Tribal entities. In the eligibility language, NIH makes clear that non-U.S. (foreign) organizations cannot apply directly, and non-U.S. components of U.S. organizations are also not eligible to apply. At the same time, foreign components are allowed as NIH defines them in its Grants Policy Statement, which generally means a U.S.-based applicant may include certain project elements or collaborations that involve a foreign component, as long as the applicant organization itself remains eligible and the arrangement fits NIH policy.

As a planning grant, the NARCH R34 is meant to support concrete preparatory work that positions an applicant to submit a future NARCH proposal that is more competitive and better aligned with community priorities. In practice, this typically includes activities such as partnership development among Tribal entities and research collaborators, community engagement and governance planning, needs and assets assessments, refinement of research aims, development of administrative and research cores or center structures, creation of data management and evaluation approaches, and establishing culturally grounded processes for oversight, ethical review, and data stewardship. The emphasis is on putting the right relationships, infrastructure concepts, and project plans in place before moving into a larger, more implementation-focused center application.

The funding opportunity is listed under NIH with Funding Opportunity Number PAR-25-441 and CFDA 93.859, and it remains open until the original closing date of 2028-07-07. The posting indicates it was created on 2025-08-26. While the summary information provided does not specify an award ceiling or the expected number of awards, it does clarify the purpose and applicant eligibility boundaries. Overall, this opportunity is best understood as a structured on-ramp for eligible AI/AN Tribal entities that want to build a future NARCH center proposal on a solid foundation of planning, community direction, and well-developed project design, without supporting clinical trial activities during this planning phase.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Native American Research Centers for Health (NARCH) Planning Grants (R34 - Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
  • This funding opportunity was created on 2025-08-26.
  • Applicants must submit their applications by 2028-07-07.
  • Eligible applicants include: Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments).
Apply for PAR 25 441

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Frequently Asked Questions (FAQs)

What is the NARCH Planning Grants program?

The Native American Research Centers for Health (NARCH) Planning Grants program is a National Institutes of Health (NIH) discretionary grant opportunity that supports early-stage planning activities. Its purpose is to help eligible American Indian and Alaska Native (AI/AN) Tribal entities do the upfront groundwork needed to later submit a strong, competitive full NARCH application.

What grant mechanism does this opportunity use?

This opportunity uses the NIH R34 planning grant mechanism, which is designed to fund structured planning and preparatory work rather than full implementation.

Are clinical trials allowed under this funding opportunity?

No. The opportunity is labeled "Clinical Trial Not Allowed." That means the grant is intended for planning and preparatory activities and is not meant to support conducting clinical trials during the planning phase.

What is the main goal of the NARCH R34 planning grant?

The main goal is to strengthen the readiness of Tribal communities and Tribal-serving organizations to develop well-designed, community-informed NARCH research center proposals. The planning work is meant to align future center proposals with AI/AN community health priorities and build a stronger foundation for future applications.

Who is eligible to apply?

The opportunity is aimed at eligible AI/AN Tribal entities, including federally recognized AI/AN Tribes, Tribal colleges and universities, Tribal health programs, and other Tribal organizations.

Can non-U.S. (foreign) organizations apply directly?

No. NIH states that non-U.S. (foreign) organizations are not eligible to apply directly for this opportunity.

Are non-U.S. components of U.S. organizations eligible to apply?

No. Non-U.S. components of U.S. organizations are also not eligible to apply under the eligibility language described.

Are foreign components allowed in any form?

Yes. Foreign components are allowed as NIH defines them in its Grants Policy Statement. In general terms, that means an eligible U.S.-based applicant may include certain project elements or collaborations involving a foreign component, as long as the applicant organization itself remains eligible and the arrangement fits NIH policy.

What types of activities are typically supported by a NARCH planning grant?

As a planning grant, the NARCH R34 is intended to support concrete preparatory work that positions the applicant for a more competitive future NARCH center proposal. Examples of activities described include partnership development among Tribal entities and research collaborators, community engagement and governance planning, needs and assets assessments, refinement of research aims, development of administrative and research cores or center structures, creation of data management and evaluation approaches, and establishing culturally grounded processes for oversight, ethical review, and data stewardship.

Is the emphasis more on relationships and planning or on running a full research center?

The emphasis is on planning and readiness: building the right relationships, outlining infrastructure concepts, and developing strong project plans before moving to a larger, more implementation-focused center application.

What is the Funding Opportunity Number (FOA) for this grant?

The Funding Opportunity Number is PAR-25-441.

What CFDA number is associated with this opportunity?

The opportunity lists CFDA 93.859.

When was this opportunity created or posted?

The posting indicates the opportunity was created on 2025-08-26.

How long is the opportunity open?

The opportunity remains open until the original closing date of 2028-07-07.

Does the summary information specify an award ceiling or the number of awards?

No. Based on the summary provided, an award ceiling and the expected number of awards are not specified.

What is this opportunity best used for?

This opportunity is best understood as a structured on-ramp for eligible AI/AN Tribal entities that want to build a future NARCH center proposal on a solid foundation of planning, community direction, and well-developed project design, without supporting clinical trial activities during the planning phase.

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