Opportunity Information: Apply for RFA AG 21 014
The National Alzheimers Coordinating Center (NACC) funding opportunity (RFA AG 21 014) is a National Institutes of Health (NIH), National Institute on Aging (NIA) cooperative agreement (U24) intended to support one national center that coordinates, standardizes, and amplifies data and collaboration across the Alzheimers Disease Research Centers (ADRCs) network. The core idea is to fund a single hub that the ADRCs and the broader Alzheimers disease (AD) and AD-related dementias (AD/ADRD) research community can rely on for high-quality national data resources, research enablement, and program-wide communication and convening. Clinical trials are not allowed under this specific U24 announcement, which signals that the work is focused on infrastructure, data coordination, and facilitation rather than testing interventions.
At a practical level, the NACC is expected to function as a national data resource by collecting and curating data submitted by the ADRCs, along with related affiliated datasets and information tied to sample repositories. This implies ongoing intake of standardized research and clinical data elements, harmonization across sites, quality control processes, documentation, and mechanisms for data access and distribution to qualified investigators. Because ADRCs operate across many institutions and populations, the coordinating center role typically involves ensuring consistency in data definitions, formats, and submission schedules so that the combined dataset can be used for large-scale analyses, replication studies, and cross-center comparisons that individual sites cannot easily accomplish alone.
Beyond being a repository, the opportunity frames NACC as a facilitator of current and future AD/ADRD research. In other words, the center is meant to actively enable science, not just store files. That facilitation function generally includes supporting investigators in understanding and using the data, producing data dictionaries and user guides, developing tools that make data easier to query and analyze, and helping the field anticipate emerging needs (for example, new diagnostic frameworks, biomarkers, digital measures, or evolving diversity and inclusion priorities). While the announcement text in your excerpt is high-level, the intended outcome is a national infrastructure that accelerates discovery by reducing friction in data sharing and making multi-site research more feasible and reliable.
The third major purpose is to serve as the central hub for organizing and enabling communication within and outside the ADRC program. This includes coordinating annual meetings and steering committees, which are important for aligning the ADRCs on scientific priorities, operations, data standards, and shared problem-solving. The hub role also suggests outward-facing communication to the broader AD/ADRD community, which can include dissemination of resources, updates on available datasets and documentation, and maintaining channels that help investigators, policymakers, and other stakeholders understand what the ADRC program is producing and how it can be used.
Administratively, this is a discretionary grant mechanism in the form of a cooperative agreement, meaning NIH/NIA is expected to have substantial involvement in the project compared with a typical research project grant. Cooperative agreements often come with structured governance, regular reporting, and close coordination with the agency and program leadership to ensure the center meets national needs and operates in alignment with the ADRC program. The announcement anticipates one award, reinforcing that this is intended to be a single, national coordinating entity rather than multiple regional centers.
In terms of funding scale and timing from the provided record, the award ceiling is $5,200,000, with an original application closing date of June 17, 2020, and a creation date of January 30, 2020. The eligible applicant pool is broad and includes many types of organizations: state, county, and municipal governments; special districts; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with and without 501(c)(3) status; for-profit organizations (including entities other than small businesses); small businesses; and other applicants as described in the full eligibility text. The funding is listed under CFDA 93.866 and is administered by the U.S. Department of Health and Human Services through NIH.
Overall, the opportunity is designed to maintain and evolve the national coordinating infrastructure that underpins ADRC-generated research by ensuring that data and associated resources are collected in a usable way, made accessible to the research community, and supported by strong coordination and communication structures. The emphasis is on building and sustaining a backbone for the AD/ADRD field: a trusted national data and coordination center that makes multi-site research faster, more consistent, and more impactful, without conducting clinical trials under this award.Apply for RFA AG 21 014
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "National Alzheimers Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
- This funding opportunity was created on Jan 30, 2020.
- Applicants must submit their applications by Jun 17, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $5,200,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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