Opportunity Information: Apply for HRSA 23 083
The Life Course Translational Research Network (LCT-RN) grant opportunity (HRSA-23-083) is a FY 2023 cooperative agreement from the Health Resources and Services Administration (HRSA), focused on building and sustaining a national, interdisciplinary, multi-site research platform that can rapidly move life course intervention research into real-world practice. The core idea is to strengthen the infrastructure and collaborations needed to run timely, innovative, high-quality applied studies that do not stop at generating findings, but actively support translation of those findings into public health and maternal and child health (MCH) programs. The network is intended to promote child health and health equity across the lifespan, with results that directly inform HRSA Maternal and Child Health Bureau (MCHB) program planning, policymaking, and evidence-based practice through a life course lens.
In practical terms, the LCT-RN is meant to support research that views child health as shaped over time by experiences and conditions at multiple levels, including the child, family, community, and broader systems. This life course framing emphasizes identifying key developmental windows and strategic points where interventions can alter health trajectories in meaningful ways. A major priority in this funding cycle is health equity, especially research that examines how maternal, paternal, and overall family physical and mental health influence child health outcomes. The opportunity explicitly points to two-generation approaches, recognizing that improving parent and caregiver health and wellbeing can be a powerful pathway to improving child outcomes and interrupting intergenerational cycles of disadvantage.
Over a five-year project period, the awardee is expected to expand and strengthen a collaborative national network that accelerates translation from research to practice while also working to reduce disparities in MCH populations. The network must conduct at least five intervention research studies grounded in life course theory, designed around critical life stages, and structured so that successful approaches can realistically be adopted in public health settings. Beyond conducting studies, the program expects the awardee to build strategic partnerships that shape research priorities and ensure the work responds to the needs of underserved communities. Another major requirement is workforce development: the network must train and mentor at least 10 junior or new investigators each year, including investigators from underserved communities and/or minority-serving institutions, helping grow the next generation of life course and translational MCH researchers.
Dissemination and measurable impact are also central expectations. The LCT-RN is required to regularly share findings, including producing at least five peer-reviewed publications per year, and to evaluate how its research influences programs, practices, and policy. The emphasis is not simply on academic output, but on demonstrating that the network is moving evidence into action and supporting decision-making in MCH systems. The LCT-RN is also expected to collaborate with HRSA MCHB-funded programs to identify priority topics, implement multi-site studies, and support translation activities that make results usable for practitioners and policymakers.
Eligibility is limited to public or nonprofit institutions of higher learning and public or private nonprofit agencies that conduct research or run programs related to maternal and child health and/or services for children with special health care needs, consistent with 42 CFR 51a.3(b). Faith-based and community-based organizations, tribes, and tribal organizations may apply if they meet the eligibility requirements. Applicants that are nonprofits must provide proof of nonprofit status (noted as Attachment 5 in the application package). Foreign entities cannot apply on their own; a foreign applicant must be affiliated with a US entity that has a US EIN recognized by HRSA in order to be considered eligible. The opportunity anticipates a single award (Expected Awards: 1) with an annual award ceiling of $800,000. The original application closing date for this cycle was April 10, 2023.Apply for HRSA 23 083
- The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Life Course Translational Research Network (LCT-RN)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.110.
- This funding opportunity was created on 2023-01-09.
- Applicants must submit their applications by 2023-04-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $800,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others.
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Life Course Translational Research Network (LCT-RN) Grant (HRSA-23-083) - FAQs
What is the LCT-RN grant opportunity (HRSA-23-083)?
The Life Course Translational Research Network (LCT-RN) grant opportunity (HRSA-23-083) is a FY 2023 cooperative agreement from the Health Resources and Services Administration (HRSA). It is focused on building and sustaining a national, interdisciplinary, multi-site research platform that can rapidly move life course intervention research into real-world practice.
What is the primary purpose of the LCT-RN?
The primary purpose is to strengthen the infrastructure and collaborations needed to run timely, innovative, high-quality applied studies and to actively support translation of findings into public health and maternal and child health (MCH) programs. The intent is for results to directly inform HRSA Maternal and Child Health Bureau (MCHB) program planning, policymaking, and evidence-based practice through a life course lens.
What does "life course" mean in the context of this opportunity?
In this opportunity, the life course approach frames child health as shaped over time by experiences and conditions at multiple levels, including the child, family, community, and broader systems. It emphasizes identifying key developmental windows and strategic points where interventions can alter health trajectories in meaningful ways.
What kinds of research does the network support?
The network is intended to support applied intervention research grounded in life course theory, designed around critical life stages, and structured so that successful approaches can realistically be adopted in public health settings. The program is oriented toward studies that do not stop at generating findings, but also support moving evidence into practice.
What populations and outcomes are emphasized?
The opportunity emphasizes maternal and child health (MCH) populations and aims to promote child health and health equity across the lifespan. It also references programs and services related to children with special health care needs.
Is health equity a required focus?
Health equity is described as a major priority in this funding cycle, with an emphasis on reducing disparities in MCH populations and ensuring research responds to the needs of underserved communities.
What is the stated priority topic area for this funding cycle?
A major priority is research examining how maternal, paternal, and overall family physical and mental health influence child health outcomes, including two-generation approaches that improve parent and caregiver health and wellbeing as a pathway to better child outcomes.
What are "two-generation approaches" in this opportunity?
Two-generation approaches are described as strategies that recognize parent and caregiver health and wellbeing as a powerful pathway to improving child outcomes and interrupting intergenerational cycles of disadvantage.
How long is the project period?
The expected project period is five years.
How many intervention studies must the network conduct?
The awardee is expected to conduct at least five intervention research studies grounded in life course theory.
What expectations exist for partnerships and collaboration?
The awardee is expected to expand and strengthen a collaborative national network and build strategic partnerships that help shape research priorities and ensure the work responds to the needs of underserved communities. The network is also expected to collaborate with HRSA MCHB-funded programs to identify priority topics, implement multi-site studies, and support translation activities that make results usable for practitioners and policymakers.
What are the workforce development requirements?
The network must train and mentor at least 10 junior or new investigators each year. This includes investigators from underserved communities and/or minority-serving institutions, with the goal of growing the next generation of life course and translational MCH researchers.
What dissemination outputs are expected?
The LCT-RN is required to regularly share findings, including producing at least five peer-reviewed publications per year.
Does the opportunity require showing real-world impact beyond publications?
Yes. The opportunity emphasizes measurable impact and expects the network to evaluate how its research influences programs, practices, and policy. The focus is on moving evidence into action and supporting decision-making in MCH systems, not solely academic output.
Who is eligible to apply?
Eligibility is limited to public or nonprofit institutions of higher learning and public or private nonprofit agencies that conduct research or run programs related to maternal and child health and/or services for children with special health care needs, consistent with 42 CFR 51a.3(b).
Can faith-based or community-based organizations apply?
Yes. Faith-based and community-based organizations may apply if they meet the eligibility requirements.
Can tribes or tribal organizations apply?
Yes. Tribes and tribal organizations may apply if they meet the eligibility requirements.
What documentation is required for nonprofit applicants?
Nonprofit applicants must provide proof of nonprofit status, noted as Attachment 5 in the application package.
Are foreign entities eligible?
Foreign entities cannot apply on their own. A foreign applicant must be affiliated with a US entity that has a US EIN recognized by HRSA in order to be considered eligible.
How many awards does HRSA expect to make?
The opportunity anticipates a single award (Expected Awards: 1).
What is the annual award amount?
The annual award ceiling is $800,000.
What is the application deadline listed for this cycle?
The original application closing date for this cycle was April 10, 2023.
What makes this a cooperative agreement?
The opportunity is described as a cooperative agreement, and it explicitly expects collaboration with HRSA MCHB-funded programs to identify priorities, implement multi-site studies, and support translation activities. (Additional details about federal involvement are not provided in the information here.)
What does "translation from research to practice" mean here?
In this opportunity, translation means designing and carrying out intervention research in ways that support adoption of effective approaches in real public health settings, and ensuring findings are usable for practitioners and policymakers in MCH systems.
What does the network need to build, beyond individual studies?
Beyond conducting at least five studies, the network is expected to build and sustain a national, interdisciplinary, multi-site research platform, strengthen collaborations, develop partnerships that guide priorities, mentor new investigators, and disseminate findings while tracking how the work affects programs, practices, and policy.
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