Opportunity Information: Apply for PAR 17 314
Global Brain and Nervous System Disorders Research Across the Lifespan (R01) is a National Institutes of Health (NIH) funding opportunity (PAR-17-314) that supports full-scale R01 research grants focused on brain and broader nervous system function and disorders across the entire life course. The central aim is to stimulate innovative, high-impact projects that are directly relevant to low- and middle-income countries (LMICs), while also strengthening meaningful scientific collaboration across countries and institutions.
A key feature of this announcement is its emphasis on collaborative, cross-national research partnerships. Applications are encouraged that bring together U.S.-based scientists and researchers working in LMICs to address shared scientific questions in ways that reflect LMIC realities, needs, and constraints. In addition, the FOA allows an important pathway for upper middle-income country (UMIC) investigators: UMIC scientists may partner directly with institutions in other LMICs, and they may do so either with a U.S. partner or without one. The FOA relies on the World Bank country income classifications to define LMIC and UMIC status, using the World Bank listing of country and lending groups.
The scientific scope is intentionally broad. Projects may address neurological disorders as well as mental, behavioral, alcohol-related, and substance use disorders, provided the research is relevant to LMIC contexts. The FOA also spans the full research spectrum, meaning proposals can range from basic and mechanistic studies through clinical, epidemiological, and translational research, all the way to implementation research that tests real-world strategies for delivering or scaling effective interventions. The "across the lifespan" framing signals that NIH is interested in research covering any life stage, such as prenatal and early childhood development, adolescence, adulthood, and aging, including how risk and resilience factors, exposures, and interventions differ by developmental period.
Eligibility is expansive and includes many organizational types that commonly participate in NIH-funded work. Beyond universities and research institutes, eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The FOA also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, non-U.S. entities (foreign organizations), and U.S. territories or possessions. This broad eligibility aligns with the FOA's goal of encouraging diverse partnerships and strengthening research capacity where the burden of nervous system disorders can be high and resources may be limited.
From an administrative standpoint, this is a discretionary grant opportunity under NIH, categorized under environment and health-related assistance listings, with CFDA numbers 93.113, 93.173, 93.242, 93.321, 93.853, 93.866, 93.867, and 93.989. The opportunity was created on 2017-06-13 and listed an original closing date of 2018-06-19 in the source information provided. The listing does not specify an award ceiling or expected number of awards in the excerpt, so applicants would typically consult the full FOA and associated NIH institute guidance for budget expectations, project period norms, and review considerations.
In practical terms, an application responsive to this FOA would clearly explain why the research question matters for LMIC populations, demonstrate genuine collaboration across the participating institutions, and describe an approach that is scientifically rigorous while also feasible within the intended settings. Strong proposals commonly clarify the roles and contributions of each partner, plans for data management and sharing where appropriate, and how the work could produce knowledge or tools that improve understanding, prevention, diagnosis, treatment, or delivery of care for brain and nervous system disorders in LMIC contexts.Apply for PAR 17 314
- The National Institutes of Health in the environment, health sector is offering a public funding opportunity titled "Global Brain and Nervous System Disorders Research Across the Lifespan (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.173, 93.242, 93.321, 93.853, 93.866, 93.867, 93.989.
- This funding opportunity was created on 2017-06-13.
- Applicants must submit their applications by 2018-06-19. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (SBIR R44) Apply for RFA ES 17 007 Funding Number: RFA ES 17 007 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Organotypic Culture Models developed from Experimental Animals for Chemical Toxicity Screening (R43) Apply for RFA ES 17 008 Funding Number: RFA ES 17 008 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Population-Based Model Organism Research for G x E Exploration in Complex Disease Outcomes (R01 Clinical Trial Not Allowed) Apply for RFA ES 17 009 Funding Number: RFA ES 17 009 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $499,999 |
| Immuno-Oncology Translational Network (IOTN): Cancer Immunotherapy Research Projects (U01) Apply for RFA CA 17 045 Funding Number: RFA CA 17 045 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $500,000 |
| Outstanding New Environmental Scientist (ONES) Award (R01 Clinical Trial Optional) Apply for RFA ES 18 001 Funding Number: RFA ES 18 001 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Environmental Health Sciences Core Centers (EHS CC) (P30 Clinical Trial Optional) Apply for RFA ES 18 003 Funding Number: RFA ES 18 003 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Transition to Independent Environmental Health Research (TIEHR) Career Transition Award (K01 Clinical Trial Required) Apply for PAR 18 261 Funding Number: PAR 18 261 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Transition to Independent Environmental Health Research (TIEHR) Career Transition Award (K01 Clinical Trial Not Allowed) Apply for PAR 18 291 Funding Number: PAR 18 291 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| The Role of the Microbiome in the Developmental Origins of Health and Disease (DOHaD) (R01 Clinical Trial Not Allowed) Apply for RFA ES 18 005 Funding Number: RFA ES 18 005 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $400,000 |
| Revolutionizing Innovative, Visionary Environmental health Research (RIVER) (R35 Clinical Trial Not Allowed) Apply for RFA ES 18 004 Funding Number: RFA ES 18 004 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $600,000 |
| SBIR E-learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed) Apply for RFA ES 18 006 Funding Number: RFA ES 18 006 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $100,000 |
| Exposure Analysis Services for the Environmental Influences on Child Health Outcomes (ECHO) Program (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 783 Funding Number: PA 18 783 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Novel Approaches for Characterizing Exposure and Response to Engineered Nanomaterials (R43 Clinical Trials Not Allowed) Apply for RFA ES 18 008 Funding Number: RFA ES 18 008 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43)(Clinical Trial Optional) Apply for PAR 18 901 Funding Number: PAR 18 901 Agency: National Institutes of Health Category: Environment, Health Funding Amount: Case Dependent |
| Telomeres as Sentinels of Environmental Exposures, Psychosocial Stress, and Disease Susceptibility: A Methods Comparison Study (U01 Clinical Trial Optional) Apply for RFA AG 19 023 Funding Number: RFA AG 19 023 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $200,000 |
| Research Network on Telomeres as Sentinels of Environmental Exposures, Psychosocial Stress, and Disease Susceptibility (U24 Clinical Trial Not Allowed) Apply for RFA AG 19 022 Funding Number: RFA AG 19 022 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $345,000 |
| Human Health Exposure Analysis Resource: Data Repository, Analysis and Science Center (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 014 Funding Number: RFA ES 18 014 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,700,000 |
| Human Health Exposure Analysis Resource: Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA ES 18 010 Funding Number: RFA ES 18 010 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $700,000 |
| Human Health Exposure Analysis Resource: UnTargeted Exposure Analysis Laboratories (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 012 Funding Number: RFA ES 18 012 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,500,000 |
| Human Health Exposure Analysis Resource: Targeted Exposure Analysis Laboratories (U2C Clinical Trial Not Allowed) Apply for RFA ES 18 011 Funding Number: RFA ES 18 011 Agency: National Institutes of Health Category: Environment, Health Funding Amount: $1,500,000 |
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